Nicole J. Guselle, B.Sc., Ph.D.

Department of Pathology and Microbiology
Atlantic Veterinary College, University of Prince Edward Island
550 University Avenue
Charlottetown, PE
Canada C1A 4P3


Research Interests:
Prior to doing my Ph.D., I worked as a research technician at the University of Calgary on a wide array of Giardia and Cryptosporidium projects. My dissertation focused on prevalence Giardia and Cryptosporidium in Alberta swine and survival in the farm setting. I am now at the Atlantic Veterinary College as a senior research associate and have being working with a microsporidian of salmonids, Loma salmonae. The current research foci are on alternative treatments, vaccine development and evaluating parasite persistence in the environment via biomarkers. I also have an interest in anisakid roundworms in commercially produced fish and I maintain an interest in Giardia and Cryptosporidium research.

Keywords: microsporidians, fish, vaccine, alternative treatment, Giardia, Cryptosporidium.

Recent Publications:

Guselle NJ, Speare DJ and Markham RJF. 2010. Efficacy of ProVale™, a yeast β-1, 3/1, 6-D-glucan product, administered intraperitoneally and orally, in inhibiting xenoma formation by the microsporidian, Loma salmonae on rainbow trout gills. North American Journal of Aquaculture. 72: 65-72.

Speare DJ, Markham RJF and Guselle NJ. 2007. Development of an effective whole-spore antimicrosporidial vaccine: protection of rainbow trout (Oncorhynchus mykiss) from xenoma formation during Microsporidial Gill Disease using a low-virulence strain of Loma salmonae. Clinical and Vaccine Immunology. 14: 1652-1654.

Uehlinger FD, O’Handley RM, Greenwood SJ, Guselle NJ, Gabor L.J., Van Velsen CM, Steuart RF and Barkema HW. 2007. Efficacy of vaccination in preventing giardiasis in calves. Journal of Veterinary Parasitology. 146: 182-188.

Guselle NJ, Markham RJF and Speare DJ. 2007. Timing of intraperitoneal administration β-1,3 / 1,6 glucan to rainbow trout, Oncorhynchus mykiss (Walbaum), affects protection against the microsporidian Loma salmonae. Journal of Fish Diseases. 30:111-116.

Guselle NJ, Markham RJF and Speare DJ. 2006. Intraperitoneal administration of β-1, 3 / 1, 6 glucan to rainbow trout, Oncorhynchus mykiss (Walbaum), protects against Loma salmonae. Journal of Fish Diseases. 29:375-381.

Van Herk FH, McAllister TA, Cockwill CL, Guselle N, Larney FJ, Miller JJ, and Olson ME. 2004. Inactivation of Giardia cysts and Cryptosporidium oocysts in beef feedlot manure by thermophilic windrow composting. Compost Science & Utilization 12:235-241.

Guselle NJ, Appelbee AJ and Olson ME. 2003. Biology of Cryptosporidium parvum in pigs: from weaning to market. Veterinary Parasitology. 113:7-18.